The New York Red Bulls will meet LA Galaxy for the 46th time in league play and 22nd time in Los Angeles.
Head Coach Gerhard Struber will send the following Starting XI onto the field at Dignity Health Sports Park.
Brazilian goalkeeper Carlos Coronel will start on goal.
In defense, Struber will go with center-backs Aaron Long, Amro Tarek and Sean Nealis.
While in the midfield, Captain Sean Davis will be joined by Cristian Cásseres Jr. and Caden Clark.
Florian Valot and Andrew Gutman will deploy in the flanks for RBNY.
Up top, Brian White and Fábio get the nod as they did in the home opener against Sporting Kansas City.
Youba Diarra will miss the game due to a hamstring injury.
On the bench, Struber will count with Ryan Meara, Dru Yearwood, Cameron Harper, Tom Barlow, Frankie Amaya, Kyle Duncan, Andrés Reyes, Danny Royer and John Tolkin.
The game will have coverage on FS1, FOX Deportes and New York Red Bulls Radio in English and Spanish via TuneIn, the New York Red Bulls app and NewYorkRedBulls.com.
New York Red Bulls Radio begins at 5 p.m. EST with Countdown to Kickoff, presented by Honda, hosted by Matt Harmon and Steve Jolley. Stefano Fusaro will carry the Spanish play-by-play responsibilities, beginning at 5:30 p.m. EST.